简化放射免疫分析法与气液色谱法测定尿醛固酮的比较。

Comparison of a simplified radioimmunoassay with a gas-liquid chromatographic method for urinary aldosterone.

作者信息

Etienne J, Pardaens Y

出版信息

Clin Chim Acta. 1976 Oct 15;72(2):201-4. doi: 10.1016/0009-8981(76)90073-5.

Abstract

A simplified radioimmunoassay for the measurement of aldosterone in urine, requiring only an extraction without any further purification is described. The results obtained on 47 urine specimens were compared with those obtained by a gas-liquid chromatographic method. An excellent correlation was found (r = 0.932) and values obtained by both methods were similar so that this RIA has been satisfactorily adopted in our laboratory for one year. Some discrepancies, however, led us to consider the problem of preservation and storage of biological fluids.

摘要

本文描述了一种简化的尿液醛固酮放射免疫测定法，该方法仅需进行萃取，无需进一步纯化。将47份尿液标本的测定结果与气液色谱法的测定结果进行了比较。发现两者具有极好的相关性（r = 0.932），且两种方法得到的值相似，因此该放射免疫测定法已在我们实验室令人满意地采用了一年。然而，一些差异使我们考虑生物体液的保存和储存问题。