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一种测定生物体液中短链脂肪酸水平的简单定量方法。

A simple quantitative method to determine short chain fatty acid levels in biological fluids.

作者信息

Whitehead J S, Kim Y S, Prizont R

出版信息

Clin Chim Acta. 1976 Nov 1;72(3):315-8. doi: 10.1016/0009-8981(76)90193-5.

DOI:10.1016/0009-8981(76)90193-5
PMID:975584
Abstract

A simple method has been developed for quantitative acetic, propionic, isobutyric, butyric, isovaleric, valeric, isocaproic, and caproic acids in intestinal fluids, feces and blood. The method utilizes extraction with ether and gas chromatography. It is accurate over a wide range of SCFA concentrations and appears to be applicable to any biological fluid.

摘要

已开发出一种简单方法,用于定量测定肠液、粪便和血液中的乙酸、丙酸、异丁酸、丁酸、异戊酸、戊酸、异己酸和己酸。该方法采用乙醚萃取和气相色谱法。在广泛的短链脂肪酸浓度范围内该方法都很准确,并且似乎适用于任何生物流体。

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A simple quantitative method to determine short chain fatty acid levels in biological fluids.一种测定生物体液中短链脂肪酸水平的简单定量方法。
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引用本文的文献

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Butyrate production from dietary fibre and protection against large bowel cancer in a rat model.大鼠模型中膳食纤维产生丁酸盐及对大肠癌的预防作用
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Glycoprotein degradation in the blind loop syndrome: identification of glycosidases in jejunal contents.盲袢综合征中的糖蛋白降解:空肠内容物中糖苷酶的鉴定
J Clin Invest. 1981 Feb;67(2):336-44. doi: 10.1172/JCI110040.
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Carbohydrate fermentation in the human colon and its relation to acetate concentrations in venous blood.人体结肠中的碳水化合物发酵及其与静脉血中乙酸盐浓度的关系。
J Clin Invest. 1985 May;75(5):1448-54. doi: 10.1172/JCI111847.