温度对离体人真皮和皮下组织光学特性的影响。

Effect of temperature on the optical properties of ex vivo human dermis and subdermis.

作者信息

Laufer J, Simpson R, Kohl M, Essenpreis M, Cope M

机构信息

University College London, Department of Medical Physics and Bioengineering, UK.

出版信息

Phys Med Biol. 1998 Sep;43(9):2479-89. doi: 10.1088/0031-9155/43/9/004.

DOI:10.1088/0031-9155/43/9/004

PMID:9755940

Abstract

The effect of temperature on the optical properties of human dermis and subdermis as a function of near-infrared wavelength has been studied between 25 degrees C and 40 degrees C. Measurements were performed ex vivo on a total of nine skin samples taken from the abdomen of three individuals. The results show a reproducible effect of temperature on the transport scattering coefficient of dermis and subdermis. The relative change of the transport scattering coefficient showed an increase for dermis ((4.7+/-0.5) x 10(-3) degrees C(-1)) and a decrease for subdermis ((-1.4+/-0.28) x 10(-3) degrees C(-1)). Note that the magnitude of the temperature coefficient of scattering was greater for dermis than subdermis. A reproducible effect of temperature on the absorption coefficient could not be found within experimental errors. System reproducibility in transport scattering coefficient with repeated removal and repositioning of the same tissue sample at the same temperature was excellent at +/-0.35% for all measurements. This reproducibility enabled such small changes in scattering coefficient to be detected.

摘要

研究了在25摄氏度至40摄氏度之间，温度对人体真皮和皮下组织光学特性随近红外波长变化的影响。对取自三名个体腹部的总共九个皮肤样本进行了离体测量。结果显示温度对真皮和皮下组织的输运散射系数有可重复的影响。输运散射系数的相对变化显示，真皮增加（(4.7±0.5)×10⁻³摄氏度⁻¹），皮下组织减少（(-1.4±0.28)×10⁻³摄氏度⁻¹）。注意，真皮散射的温度系数幅度大于皮下组织。在实验误差范围内未发现温度对吸收系数有可重复的影响。在相同温度下对同一组织样本进行重复移除和重新定位时，输运散射系数的系统重现性极佳，所有测量的误差为±0.35%。这种重现性使得能够检测到散射系数如此小的变化。