D'Amato A, Montesani C, Casagrande M, De Milito R, Pronio A, Ribotta G
Clinica Chirurgica VI, Policlinico Umberto I, Universita La Sapienza, Roma, Italy.
Hepatogastroenterology. 1998 Jul-Aug;45(22):1135-40.
BACKGROUND/AIMS: Pancreatico-duodenectomy (PD) is nowadays a widely performed operation which still carries a risk of some morbidity and mortality due to leakage of the Pancreatico-jejunostomy. The aim of the present paper is to describe critically the experience of a surgical team with a large number of consecutive non-selective PDs, where the same surgical procedure was adopted in all cases to manage the pancreatic stump.
Sixty six Whipple/Child PDs and 4 Traverso-Longmire (Duodenum Preserving PD) were performed between 1974 and 1993, by the same surgical team in our surgical department. The management of the pancreatic stump was always the same: a hand-made end-to-side mucomucosal Wirsung-jejunostomy, completed by a second layer between pancreatic capsula and jejunal sero-muscular wall.
The overall mortality was 7.1% (5 cases). Only one death could be ascribed to pancreatico-jejunostomy related complications (post-operative acute pancreatitis). Specific morbidity was 12.6% (9 cases). Only one complication was related to the Wirsung-jejunostomy (leakage of the anastomosis, treated by a "sleeve" end-to-end pancreato-jejunostomy). Long-term patency of the anastomosis was shown by ERCP.
Even if this anastomotic technique requires a little more time and attention by the surgeon, we think that the low incidence of pancreatico-jejunal anastomosis related complications represents a validation of the method, and a motivation to adopt this anastomotic technique. The long-term patency of the muco-mucosal Wirsung-jejunostomy is another valid argument that supports this kind of management of the pancreatic stump after PD.
背景/目的:胰十二指肠切除术(PD)如今是一种广泛开展的手术,但由于胰肠吻合口漏,仍存在一定的发病和死亡风险。本文旨在批判性地描述一个手术团队大量连续进行非选择性PD的经验,所有病例均采用相同的手术方法处理胰腺残端。
1974年至1993年间,我们外科的同一手术团队进行了66例Whipple/Child PD和4例Traverso-Longmire(保留十二指肠的PD)手术。胰腺残端的处理方法始终相同:手工制作端侧黏膜对黏膜的胰管空肠吻合术,在胰腺包膜和空肠浆肌层之间完成第二层缝合。
总死亡率为7.1%(5例)。只有1例死亡可归因于胰肠吻合口相关并发症(术后急性胰腺炎)。特定发病率为12.6%(9例)。只有1例并发症与胰管空肠吻合术有关(吻合口漏,通过“套管”端端胰肠吻合术治疗)。ERCP显示吻合口长期通畅。
即使这种吻合技术需要外科医生花费更多时间和精力,但我们认为胰肠吻合口相关并发症的低发生率证明了该方法的有效性,也是采用这种吻合技术的一个动力。黏膜对黏膜的胰管空肠吻合术的长期通畅是支持PD术后这种胰腺残端处理方式的另一个有力论据。