Hulth A, Johnell O
Clin Orthop Relat Res. 1976 Oct(120):260-3.
Skeletal trauma in rats (tibial and femur fractures) stimulates bone marrow and thymus to increased mitotic activity during the first 2-3 days after the fracture. The stimulation is roughly of the same degree as that described in earlier investigations on the effects of calcium ion injections and moderate or major hemorrhages. The cause of increased mitotic level might be due to the release of kinins from the fracture area, factors which are known to stimulate mitoses of the bone marrow and thymus.
大鼠的骨骼创伤（胫骨和股骨骨折）会在骨折后的头2至3天内刺激骨髓和胸腺，使其有丝分裂活性增加。这种刺激程度与早期关于钙离子注射以及中度或大量出血影响的研究所描述的大致相同。有丝分裂水平升高的原因可能是骨折部位释放出激肽，已知这些因子会刺激骨髓和胸腺的有丝分裂。
