Okumara K, Nogami M, Matsushima Y, Matsumura K, Nakamura K, Taguchi H, Kitagawa Y
Laboratory of Biological Chemistry, Faculty of Bioresouces, Mie University, Japan.
Biosci Biotechnol Biochem. 1998 Aug;62(8):1640-2. doi: 10.1271/bbb.62.1640.
Human NP220 (hNP220) is a novel DNA-binding nuclear protein, which has an arginine/serine-rich motif and polypyrimidine tract-binding motif, and NP220s and matrin 3 are thought to form a novel family of nuclear proteins. We have determined a chromosomal localization of the cDNA encoding human NP220 to 2p13.1-p13.2 by using fluorescence in situ hybridization. Human matrin 3 cDNA was mapped to chromosomes 1p13.1-p21.1 and 5q31.3, demonstrating that these novel nuclear proteins with similar functions are on different chromosomes.
