Olszewska-Ziaber A, Zalewski P, Olszewski J, Zielińska-Bliźniewska H, Pietkiewicz P
Kliniki Otolaryngologicznej Instytutu Chirurgii WAM w Lodzi.
Otolaryngol Pol. 1997;51 Suppl 25:353-5.
The aim of the study was the clinical examinations of the tolerance and effect of Olbas oil on nasal mucosa in healthy volunteers during permanent 4 weeks administration. 23 healthy volunteers both sexes in the age between 20-50 were investigated. This investigations consisted of: history data, general and otorhinolaryngological examination, with particular evaluation of nasal mucosa, anterior rhinomanometry, olfactometry, saccharin translocation time, microbiological cultures, histamine nasal provocation test. Besides, each patient has follow up self evaluating chart of symptoms and adverse effect from the eyes, nose, pharynx and others. All the examined persons showed a very good tolerance of Olbas oil after 28 days of inhalation.
该研究的目的是在健康志愿者连续四周使用期间，对奥尔巴斯油对鼻黏膜的耐受性和效果进行临床检查。对23名年龄在20至50岁之间的健康男女志愿者进行了调查。这项调查包括：病史数据、全身及耳鼻喉科检查，特别是对鼻黏膜的评估、前鼻测压法、嗅觉测量、糖精转运时间、微生物培养、组胺鼻激发试验。此外，每位患者都有关于眼睛、鼻子、咽部及其他部位症状和不良反应的自我评估随访图表。所有接受检查的人在吸入28天后对奥尔巴斯油均表现出非常好的耐受性。
