Villa A E, Guerrero S, Villalobos J
Institute of Nutrition and Food Technology, INTA, Santiago, Chile.
Community Dent Oral Epidemiol. 1998 Aug;26(4):249-55. doi: 10.1111/j.1600-0528.1998.tb01958.x.
The purpose of this comparative study of caries and dental fluorosis experience in Chilean children was to estimate the optimal range of fluoride concentration in tap water under conditions currently prevailing in Chile. The sample included 2431 schoolchildren 7, 12 and 15 years old, life-long residents of five communities with fluoride concentrations in their tap water in the range 0.07-1.1 mg/L. The study population received an oral clinical examination including caries experience and an enamel fluorosis evaluation of the permanent dentition (Dean's scoring system). For 15-year-old children, the DMFT index changed from 5.06 to 2.60, and for 12-year-olds it changed from 3.10 to 1.36 when fluoride water concentration changed from 0.07 to 1.10 mg/L. For 7-year-old children the dmft index correspondingly changed from 3.67 to 1.59. The relationship between DMFT for 12-year-olds and water fluoride concentration was best fitted by a logarithmic function (r2=0.98). The Community Fluorosis Index (CFI) was used to assess enamel fluorosis in the study population, and it showed a linear relationship (r2=0.983) with increasing fluoride concentration of water for the 12-year-old group. Results obtained suggest that under current Chilean conditions, the optimal range of fluoride concentration in potable water should lie in the 0.5-0.6 mg/L range.
这项关于智利儿童龋齿和氟斑牙情况的比较研究的目的是，在智利当前普遍存在的条件下，估算自来水中氟化物浓度的最佳范围。样本包括2431名7岁、12岁和15岁的学童，他们是五个社区的长期居民，这些社区自来水中的氟化物浓度在0.07 - 1.1毫克/升范围内。研究人群接受了口腔临床检查，包括龋齿情况检查以及对恒牙的釉质氟斑牙评估（迪恩评分系统）。当氟水浓度从0.07毫克/升变为1.10毫克/升时，15岁儿童的DMFT指数从5.06变为2.60，12岁儿童的DMFT指数从3.10变为1.36。对于7岁儿童，dmft指数相应地从3.67变为1.59。12岁儿童的DMFT与水氟浓度之间的关系最适合用对数函数拟合（r2 = 0.98）。社区氟斑牙指数（CFI）用于评估研究人群中的釉质氟斑牙情况，对于12岁组，它与水氟浓度升高呈线性关系（r2 = 0.983）。所得结果表明，在智利当前条件下，饮用水中氟化物浓度的最佳范围应在0.5 - 0.6毫克/升之间。
