Turunen T, Peltola J, Helenius H, Yli-Urpo A, Happonen R P
Department of Oral and Maxillofacial Surgery, Institute of Dentistry, University of Turku, Finland.
Clin Oral Implants Res. 1997 Apr;8(2):96-102. doi: 10.1034/j.1600-0501.1997.080204.x.
The effect of bioactive glass (BG) and calcium carbonate (CC) granules on bone formation around titanium and BG implants projecting into the medullary space of rabbit tibia was studied. The bone marrow tissue was removed and the medullary space was filled either with BG or CC (Biocoral) granules (phi 630-800 microns). Conical titanium and BG implants were inserted into the holes drilled in compact bone using the press fit-technique. Histomorphometry was used to measure the bone-biomaterial area in a 1.0 mm wide zone around the head of the implant and the contact between formed bone and implant. Significantly larger bone-biomaterial area was obtained around titanium implants using BG than CC granules while no difference was found in connection of BG implants. Better bone-implant contact was achieved with BG implants than with titanium implants regardless of the type of granules used. The results indicate that BG may prove to be useful as filler and coating material in connection of implants projecting into bone cavities.
研究了生物活性玻璃（BG）和碳酸钙（CC）颗粒对植入兔胫骨骨髓腔的钛和BG植入物周围骨形成的影响。去除骨髓组织，并用BG或CC（生物珊瑚）颗粒（直径630 - 800微米）填充骨髓腔。使用压配技术将锥形钛和BG植入物插入致密骨中钻出的孔中。组织形态计量学用于测量植入物头部周围1.0毫米宽区域内的骨-生物材料面积以及形成的骨与植入物之间的接触情况。与使用CC颗粒相比，使用BG颗粒时钛植入物周围获得的骨-生物材料面积显著更大，而BG植入物周围未发现差异。无论使用何种颗粒类型，BG植入物比钛植入物实现了更好的骨-植入物接触。结果表明，BG可能被证明是作为植入骨腔的植入物的填充和涂层材料有用。
