• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Role of drug disposition in drug hypersensitivity: a chemical, molecular, and clinical perspective.

作者信息

Park B K, Pirmohamed M, Kitteringham N R

机构信息

The Department of Pharmacology and Therapeutics, The University of Liverpool, Ashton Street Medical Building, Ashton Street, Liverpool L69 3GE, U.K.

出版信息

Chem Res Toxicol. 1998 Sep;11(9):969-88. doi: 10.1021/tx980058f.

DOI:10.1021/tx980058f
PMID:9760271
Abstract
摘要

相似文献

1
Role of drug disposition in drug hypersensitivity: a chemical, molecular, and clinical perspective.药物处置在药物超敏反应中的作用：化学、分子及临床视角
Chem Res Toxicol. 1998 Sep;11(9):969-88. doi: 10.1021/tx980058f.
2
[The hepatotoxicity of drugs].[药物的肝毒性]
Rev Med Interna Neurol Psihiatr Neurochir Dermatovenerol Med Interna. 1988 Sep-Oct;40(5):395-406.
3
[Pharmaceutical aspects of drug side effects].
Ther Umsch. 1993 Jan;50(1):37-41.
4
Metabolism and toxicity of drugs. Two decades of progress in industrial drug metabolism.药物的代谢与毒性。工业药物代谢二十年的进展。
Chem Res Toxicol. 2008 Jan;21(1):129-37. doi: 10.1021/tx7002273. Epub 2007 Dec 4.
5
The roles of drug metabolism in the pathogenesis of T-cell-mediated drug hypersensitivity.药物代谢在T细胞介导的药物超敏反应发病机制中的作用。
Curr Opin Allergy Clin Immunol. 2008 Aug;8(4):299-307. doi: 10.1097/ACI.0b013e3283079c64.
6
Nonanaphylactic drug disorders.
Clin Allergy Immunol. 2002;16:411-33.
7
[Diagnosis of drug-induced allergic reactions].[药物性过敏反应的诊断]
Tidsskr Nor Laegeforen. 2002 Jan 30;122(3):298-9.
8
Drug allergy and hypersensitivity: still a hot topic.
Allergy. 2009 Feb;64(2):179-82. doi: 10.1111/j.1398-9995.2008.01960.x.
9
Role of bioactivation in drug-induced hypersensitivity reactions.生物活化在药物诱导的超敏反应中的作用。
AAPS J. 2006 Feb 3;8(1):E55-64. doi: 10.1208/aapsj080107.
10
Role of drug metabolism for breaking tolerance and the localization of drug hypersensitivity.药物代谢在打破耐受性及药物超敏反应定位中的作用。
Toxicology. 2005 Apr 15;209(2):113-8. doi: 10.1016/j.tox.2004.12.019. Epub 2005 Jan 26.

引用本文的文献

1
The diagnosis of acute interstitial nephritis caused by infection versus antibiotic-induced interstitial nephritis: a narrative review.感染所致急性间质性肾炎与抗生素诱发的间质性肾炎的诊断：一篇叙述性综述
Clin Kidney J. 2024 Mar 4;17(4):sfae054. doi: 10.1093/ckj/sfae054. eCollection 2024 Apr.
2
Patients with naproxen-induced liver injury display T-cell memory responses toward an oxidative (S)-O-desmethyl naproxen metabolite but not the acyl glucuronide.萘普生诱导的肝损伤患者对氧化型（S）-O-去甲基萘普生代谢物表现出T细胞记忆反应，而对酰基葡萄糖醛酸则无此反应。
Allergy. 2024 Jan;79(1):200-214. doi: 10.1111/all.15830. Epub 2023 Jul 29.
3
MD Investigation on the Interaction between Carbamazepine and Two CYP Isoforms, CYP3A4 and CYP3A5.
关于卡马西平与两种 CYP 同工酶（CYP3A4 和 CYP3A5）相互作用的 MD 研究。
Int J Mol Sci. 2023 Jan 22;24(3):2188. doi: 10.3390/ijms24032188.
4
Genomic Risk Factors Driving Immune-Mediated Delayed Drug Hypersensitivity Reactions.驱动免疫介导的迟发性药物超敏反应的基因组风险因素。
Front Genet. 2021 Apr 16;12:641905. doi: 10.3389/fgene.2021.641905. eCollection 2021.
5
Dapsone- and nitroso dapsone-specific activation of T cells from hypersensitive patients expressing the risk allele HLA-B*13:01.表达风险等位基因 HLA-B*13:01 的过敏患者的 T 细胞中，对氨苯砜和亚硝氨苯砜特异性的激活。
Allergy. 2019 Aug;74(8):1533-1548. doi: 10.1111/all.13769. Epub 2019 Apr 15.
6
A derivatization-enhanced detection strategy in mass spectrometry: analysis of 4-hydroxybenzoates and their metabolites after keratinocytes are exposed to UV radiation.质谱中的衍生增强检测策略：角质形成细胞暴露于紫外线辐射后对 4-羟基苯甲酸及其代谢物的分析。
Sci Rep. 2017 Jan 6;7:39907. doi: 10.1038/srep39907.
7
The influence of the carrier molecule on amoxicillin recognition by specific IgE in patients with immediate hypersensitivity reactions to betalactams.载体分子对β-内酰胺类速发型过敏反应患者特异性IgE识别阿莫西林的影响。
Sci Rep. 2016 Oct 12;6:35113. doi: 10.1038/srep35113.
8
Basophil Reactivity as Biomarker in Immediate Drug Hypersensitivity Reactions-Potential and Limitations.嗜碱性粒细胞反应性作为速发型药物超敏反应生物标志物的潜力与局限性
Front Pharmacol. 2016 Jun 17;7:171. doi: 10.3389/fphar.2016.00171. eCollection 2016.
9
Drug Induced Liver Injury: Review with a Focus on Genetic Factors, Tissue Diagnosis, and Treatment Options.药物性肝损伤：综述及遗传因素、组织诊断和治疗选择的关注
J Clin Transl Hepatol. 2015 Jun 28;3(2):99-108. doi: 10.14218/JCTH.2015.00007. Epub 2015 Jun 15.
10
Structure-Activity Relationships of the Antitumor C5-Curcuminoid GO-Y030.抗肿瘤C5-姜黄素类似物GO-Y030的构效关系
Molecules. 2015 Aug 24;20(8):15374-91. doi: 10.3390/molecules200815374.