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颅颌面区域骨纤维异常增殖症:当前临床观点

Fibrous dysplasia of the craniomaxillofacial region: current clinical perspectives.

作者信息

Posnick J C

机构信息

Craniomaxillofacial Center, Georgetown Craniofacial Center, Georgetown University Medical Center, Washington, DC, USA.

出版信息

Br J Oral Maxillofac Surg. 1998 Aug;36(4):264-73. doi: 10.1016/s0266-4356(98)90710-0.

Abstract

Fibrous dysplasia is a benign fibro-osseous disease of bone of unknown etiology. Its occurrence in the craniomaxillofacial skeleton is frequent and varies in severity from an asymptomatic monostotic lesion to polyostotic involvement resulting in progressive functional deficit and aesthetic problems. With the advent of refined instrumentation and craniofacial surgical techniques, a more aggressive, non-disabling approach to these benign yet deforming fibro-osseous growths is possible. In some patients, complete excision of the involved bone with graft reconstruction of the resultant defect with primary autogenous bone may be possible. Lifelong continuous ongoing monitoring of the involved region is required throughout the patient's life.

摘要

骨纤维异常增殖症是一种病因不明的良性骨纤维-骨疾病。它在颅颌面骨骼中很常见,严重程度各不相同,从无症状的单骨病变到多骨受累,可导致进行性功能障碍和美学问题。随着精密器械和颅面外科技术的出现,对于这些良性但会导致畸形的纤维-骨生长,采取更积极、不致残的治疗方法成为可能。在一些患者中,有可能完全切除受累骨骼,并用自体骨对由此产生的缺损进行移植重建。在患者的一生中,都需要对受累区域进行终身持续监测。

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