Graves T, Crutcher J M
Oklahoma State Department of Health, Oklahoma City 73117, USA.
J Okla State Med Assoc. 1998 Sep;91(6):327-30.
Hantavirus Pulmonary Syndrome (HPS) is a condition of rapidly progressive pulmonary failure with a case-fatality rate of almost 50 percent. Rodents serve as the reservoir for hantaviruses and human infection occurs primarily via aerosolized virus in rodent excreta. The rodent reservoir for the disease is widespread across Oklahoma and the first case of HPS has recently been confirmed in an Oklahoma resident. Physicians should suspect HPS in a previously healthy person who develops a febrile illness and respiratory insufficiency and has potentially been exposed to the virus. Common laboratory findings include a left-shifted neutrophilic leukocytosis, elevated hematocrit and thrombocytopenia. Therapy is supportive. If HPS is suspected, the patient should be immediately transferred to a facility that can provide aggressive supportive care.
汉坦病毒肺综合征（HPS）是一种迅速进展的肺衰竭疾病，病死率近50%。啮齿动物是汉坦病毒的宿主，人类感染主要通过吸入啮齿动物排泄物中的气溶胶化病毒。该疾病的啮齿动物宿主在俄克拉荷马州广泛分布，最近一名俄克拉荷马州居民被确诊为首例HPS病例。对于先前健康、出现发热性疾病和呼吸功能不全且可能接触过该病毒的人，医生应怀疑其患有HPS。常见的实验室检查结果包括中性粒细胞左移性白细胞增多、血细胞比容升高和血小板减少。治疗以支持治疗为主。如果怀疑患有HPS，应立即将患者转至能够提供积极支持治疗的机构。
