转移性子宫平滑肌肉瘤表现为腮腺原发性肉瘤。
Metastatic uterine leiomyosarcoma presenting as a primary sarcoma of the parotid gland.
作者信息
Saiz A D, Sachdev U, Brodman M L, Deligdisch L
机构信息
Department of Pathology, The Lillian and Henry M. Stratton-Hans Popper Mount Sinai School of Medicine, New York, New York 10029, USA.
出版信息
Obstet Gynecol. 1998 Oct;92(4 Pt 2):667-8. doi: 10.1016/s0029-7844(98)00137-9.
BACKGROUND
Leiomyosarcoma of the uterus has a high metastatic potential to distant sites due to its tendency for hematogenous spread.
CASE
A 49-year-old woman presented with an enlarging parotid mass, diagnosed originally as a primary fibrosarcoma. Six years later, she developed pulmonary metastases and heavy, abnormal uterine bleeding. At hysterectomy, a uterine leiomyosarcoma, identical morphologically to the previous lesions, was identified. All tumors showed similar immunohistochemical staining, suggesting the metastatic nature of the original parotid tumor.
CONCLUSION
This rare case of uterine leiomyosarcoma, presenting as a primary parotid sarcoma, underscores the importance of considering the possibility of a uterine primary tumor when a sarcoma arises in an organ in which these tumors are unusual.
背景
子宫平滑肌肉瘤因血行播散倾向而具有较高的远处转移潜能。
病例
一名49岁女性出现腮腺肿物增大，最初诊断为原发性纤维肉瘤。6年后，她出现肺转移及大量异常子宫出血。子宫切除术中，发现一个子宫平滑肌肉瘤，其形态与先前病变相同。所有肿瘤均显示相似的免疫组化染色，提示原发腮腺肿瘤具有转移性。
结论
这例罕见的子宫平滑肌肉瘤表现为原发性腮腺肉瘤，强调了当肉瘤发生于这些肿瘤不常见的器官时，考虑子宫原发性肿瘤可能性的重要性。
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