室温硫化硅橡胶假体弹性体的物理力学和细胞毒性特性
Physicomechanical and cytotoxic properties of room temperature vulcanizing silicone prosthetic elastomers.
作者信息
Polyzois G L, Pettersen A H
机构信息
Department of Removable Prosthodontics, School of Dentistry, University of Athens, Greece.
出版信息
Acta Odontol Scand. 1998 Aug;56(4):245-8. doi: 10.1080/00016359850142871.
The physicomechanical and cytotoxic properties of two newly introduced room temperature vulcanizing (RTV) silicone prosthetic elastomers, Ideal and Silskin 2000, were investigated. Another RTV silicone, Elastosil M3500, was also investigated as a potential facial material. The in vitro cytotoxicity was assessed with the agar diffusion test and mouse fibroblast cells (L929). The properties investigated were tensile strength, percentage elongation, modulus, tear strength, hardness, and color changes (deltaE*). The properties tested were selected because of their clinical significance in fabricating facial prostheses. The results indicate that Elastosil M3500 has a better combination of high tear strength, elongation at break, and low hardness than Ideal and Silskin 2000. All materials demonstrated a low cytotoxic profile. Elastosil M3500 warrants further attention with clinical trials.
对两种新推出的室温硫化（RTV）硅酮假体弹性体Ideal和Silskin 2000的物理力学和细胞毒性特性进行了研究。另一种RTV硅酮Elastosil M3500也作为一种潜在的面部材料进行了研究。采用琼脂扩散试验和小鼠成纤维细胞（L929）评估体外细胞毒性。所研究的特性包括拉伸强度、伸长率百分比、模量、撕裂强度、硬度和颜色变化（ΔE*）。选择这些测试特性是因为它们在制造面部假体方面具有临床意义。结果表明，与Ideal和Silskin 2000相比，Elastosil M3500具有更高的撕裂强度、断裂伸长率和更低的硬度的更好组合。所有材料均表现出低细胞毒性特征。Elastosil M3500值得通过临床试验进一步关注。
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