[半胱胺在大肠杆菌细胞中诱导的蛋白质]

[Proteins induction by cysteamine in Escherichia coli cells].

作者信息

Suslov A V, Suslova I N

机构信息

B.P. Konstantinov St.-Petersburg Institute of Nuclear Physics, Academy of Sciences of Russia, Gatchina.

出版信息

Radiats Biol Radioecol. 1998 Jul-Aug;38(4):488-94.

PMID:9765666

Abstract

It was shown, what in presence of oxygen in broad interval time of treatment in E. coli cells was induced line proteins by cysteamine which are proteins SOS--repair system and heat--shock system. There are quantitative defined induction level RecA, GroEL and DnaK proteins which are members this systems. It was allowed to propose what radioprotective action of cysteamine in higher degree is defined by its characteristics as induction agent for stress systems of cells.

摘要

结果表明，在大肠杆菌细胞中，当存在氧气时，在较宽的处理时间间隔内，半胱胺可诱导SOS修复系统和热休克系统的相关蛋白。该系统的成员RecA、GroEL和DnaK蛋白存在定量确定的诱导水平。由此可以推测，半胱胺的辐射防护作用在很大程度上取决于其作为细胞应激系统诱导剂的特性。