Kneschaurek P
Klinik und Poliklinik für Strahlentherapie und Radiologische Onkologie, Technische Universität München.
Strahlenther Onkol. 1998 Sep;174(9):468-72. doi: 10.1007/BF03038625.
In HDR brachytherapy activity distributions can be achieved which were unknown in LDR brachytherapy. For this reason the classical dosage systems can only be used with caution in HDR brachytherapy.
Different simple applications are used to investigate the effect of various activity distributions on dose and integrated reference air kerma.
Within the classical LDR dosage systems dose and integrated reference air kerma were equivalent. Due to the possibility to "optimize" the activity distribution in HDR brachytherapy this is not longer the case. Different optimization algorithms and different optimization goals may lead to quite different activity distributions and different integrated reference air kerma values even if the source positions are the same. For target volume oriented optimization schemes a dosage system is described which is based on dose-volume-histograms.
A widely accepted dosage system in HDR brachytherapy is missing. The dosage system described in this paper may be useful in solving this problem.
在高剂量率近距离放射治疗中,可以实现低剂量率近距离放射治疗中未知的活度分布。因此,经典的剂量系统在高剂量率近距离放射治疗中只能谨慎使用。
使用不同的简单应用来研究各种活度分布对剂量和积分参考空气比释动能的影响。
在经典的低剂量率剂量系统中,剂量和积分参考空气比释动能是等效的。由于在高剂量率近距离放射治疗中可以“优化”活度分布,情况已不再如此。即使源位置相同,不同的优化算法和不同的优化目标也可能导致截然不同的活度分布和不同的积分参考空气比释动能值。对于以靶区体积为导向的优化方案,描述了一种基于剂量体积直方图的剂量系统。
高剂量率近距离放射治疗中缺少一种被广泛接受的剂量系统。本文描述的剂量系统可能有助于解决这一问题。