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76例不稳定型心绞痛的冠状动脉造影及心室造影表现(作者译)

[Coronarographic and ventriculographic aspects of 76 cases of unstable angina (authors transl)].

作者信息

Masini V, Vajola F, Santini M, Bordi L, Biffani G

出版信息

G Ital Cardiol. 1976;6(4):582-93.

PMID:976656
Abstract

-- Coronarographic and ventriculographic aspects of 76 patients with unstable angina were analyzed. 8 cases (10%) had normal coronary arteries, 9 (11.8%) had slight stenotic lesions (less than 50%), 59 (77.6%) had serious stenosis. The stenosis concerned only one principal branch in 22 patients (37.2%), 2 branches in 24 (40%), 3 branches in 13 (22%). In 77-79% of cases, ventricular contractility was normal. A collateral circulation was found in 58% of cases, but no link was discovered between the coronaric lesions and the clinical type of angina. The course of the illness was studied during the hospitalization and post-hospitalization period for an average observation time of 14 months (55 cases). The course of illness type depends on the number of affected branches and the myocardial contractility. In 25% of the patients with lesions in 3 branches there was an unfavourable course of illness (either infarction or death), whilst where there were lesions in one or two branches, negative results were 11% and 15% respectively. Patients with normal coronary arteries or slight stenosis had no unfavourable course of illness. In 37% of patients with altered contractility, an unfavourable course of illness was found, as against 27% with normal contractility. The presence of collateral circulation doesn't seem to influence the course the illness takes. A coronarographic examination seems to be an essential elelment in deciding on the prognosis of unstable angina.

摘要

对76例不稳定型心绞痛患者的冠状动脉造影和心室造影情况进行了分析。8例(10%)冠状动脉正常,9例(11.8%)有轻度狭窄病变(小于50%),59例(77.6%)有严重狭窄。22例患者(37.2%)的狭窄仅涉及一个主要分支,24例(40%)涉及两个分支,13例(22%)涉及三个分支。在77% - 79%的病例中,心室收缩功能正常。58%的病例发现有侧支循环,但未发现冠状动脉病变与心绞痛临床类型之间存在关联。在住院期间和出院后对病情进行了研究,平均观察时间为14个月(55例)。病情类型取决于受累分支的数量和心肌收缩力。在三个分支有病变的患者中,25%病情发展不利(发生梗死或死亡),而在一个或两个分支有病变的患者中,不良结果分别为11%和15%。冠状动脉正常或轻度狭窄的患者病情发展无不利情况。在心肌收缩力改变的患者中,37%病情发展不利,而心肌收缩力正常的患者中这一比例为27%。侧支循环的存在似乎不影响病情发展过程。冠状动脉造影检查似乎是决定不稳定型心绞痛预后的一个重要因素。

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