Masini V, Vajola F, Santini M, Bordi L, Biffani G
G Ital Cardiol. 1976;6(4):582-93.
-- Coronarographic and ventriculographic aspects of 76 patients with unstable angina were analyzed. 8 cases (10%) had normal coronary arteries, 9 (11.8%) had slight stenotic lesions (less than 50%), 59 (77.6%) had serious stenosis. The stenosis concerned only one principal branch in 22 patients (37.2%), 2 branches in 24 (40%), 3 branches in 13 (22%). In 77-79% of cases, ventricular contractility was normal. A collateral circulation was found in 58% of cases, but no link was discovered between the coronaric lesions and the clinical type of angina. The course of the illness was studied during the hospitalization and post-hospitalization period for an average observation time of 14 months (55 cases). The course of illness type depends on the number of affected branches and the myocardial contractility. In 25% of the patients with lesions in 3 branches there was an unfavourable course of illness (either infarction or death), whilst where there were lesions in one or two branches, negative results were 11% and 15% respectively. Patients with normal coronary arteries or slight stenosis had no unfavourable course of illness. In 37% of patients with altered contractility, an unfavourable course of illness was found, as against 27% with normal contractility. The presence of collateral circulation doesn't seem to influence the course the illness takes. A coronarographic examination seems to be an essential elelment in deciding on the prognosis of unstable angina.
对76例不稳定型心绞痛患者的冠状动脉造影和心室造影情况进行了分析。8例（10%）冠状动脉正常，9例（11.8%）有轻度狭窄病变（小于50%），59例（77.6%）有严重狭窄。22例患者（37.2%）的狭窄仅涉及一个主要分支，24例（40%）涉及两个分支，13例（22%）涉及三个分支。在77% - 79%的病例中，心室收缩功能正常。58%的病例发现有侧支循环，但未发现冠状动脉病变与心绞痛临床类型之间存在关联。在住院期间和出院后对病情进行了研究，平均观察时间为14个月（55例）。病情类型取决于受累分支的数量和心肌收缩力。在三个分支有病变的患者中，25%病情发展不利（发生梗死或死亡），而在一个或两个分支有病变的患者中，不良结果分别为11%和15%。冠状动脉正常或轻度狭窄的患者病情发展无不利情况。在心肌收缩力改变的患者中，37%病情发展不利，而心肌收缩力正常的患者中这一比例为27%。侧支循环的存在似乎不影响病情发展过程。冠状动脉造影检查似乎是决定不稳定型心绞痛预后的一个重要因素。
