Picard A, Cheliout Heraut F, Bouskraoui M, Lemoine M, Lacert P, Delattre J
Service de Neurologie et de Rééducation Infantile, Hôpital Raymond Poincaré, Garches, France.
Dev Med Child Neurol. 1998 Sep;40(9):595-9. doi: 10.1111/j.1469-8749.1998.tb15424.x.
To determine the relation between developmental dysphasia and EEG anomalies during sleep, we compared 52 subjects with dysphasia with a control group of 20 children by using the ambulatory EEG method. Whereas 50% of the children with dysphasia experienced paroxysmal activity (PA), only two of the control group did. It is likely that paroxysmal abnormalities and language impairment are related to architectural dysplasia and neuron-migration disturbances. PA is frequent in subjects with receptive developmental dysphasia and may be the cause of language deterioration. When the occurrence of paroxysmal abnormalities during sleep is higher than 8% of total sleep time, we suggest the use of antiepileptic drugs.
为了确定发育性语言障碍与睡眠期间脑电图异常之间的关系，我们采用动态脑电图方法，将52名语言障碍受试者与20名儿童组成的对照组进行了比较。患有语言障碍的儿童中有50%出现阵发性活动（PA），而对照组中只有两人出现。阵发性异常和语言障碍可能与结构发育异常和神经元迁移紊乱有关。PA在接受性发育性语言障碍患者中很常见，可能是语言退化的原因。当睡眠期间阵发性异常的发生率高于总睡眠时间的8%时，我们建议使用抗癫痫药物。
