首发及慢性精神分裂症患者神经心理功能的性别差异。
Sex differences in neuropsychological functioning of first-episode and chronically ill schizophrenic patients.
作者信息
Hoff A L, Wieneke M, Faustman W O, Horon R, Sakuma M, Blankfeld H, Espinoza S, DeLisi L E
机构信息
University of California, Davis-Napa Psychiatric Research Center, Napa State Hospital 94558, USA.
出版信息
Am J Psychiatry. 1998 Oct;155(10):1437-9. doi: 10.1176/ajp.155.10.1437.
OBJECTIVE
The purpose of this study was to determine whether men and women with schizophrenia demonstrate differences in cognitive abilities.
METHOD
Two cohorts of patients with schizophrenia, an acute first-episode and a chronically hospitalized group, were evaluated with a neuropsychological battery and compared with a normal group of subjects.
RESULTS
After adjustment for age, age at onset, and premorbid IQ, male chronic patients performed worse than female chronic patients on measures of visual memory. These differences were eliminated after control for symptom severity. No other differences were found in cognitive function between men and women in either cohort.
CONCLUSIONS
Sex differences in cognitive function in schizophrenic patients are not robust findings.
目的
本研究旨在确定精神分裂症男性和女性在认知能力上是否存在差异。
方法
对两组精神分裂症患者，即急性首发组和慢性住院组，进行了一套神经心理测试，并与一组正常受试者进行比较。
结果
在对年龄、发病年龄和病前智商进行调整后，男性慢性患者在视觉记忆测试中的表现比女性慢性患者差。在控制症状严重程度后，这些差异消失。在任何一组中，男性和女性在认知功能上均未发现其他差异。
结论
精神分裂症患者认知功能的性别差异并非确凿的研究结果。
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