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[免疫功能正常患者在严重鼠伤寒沙门氏菌菌血症期间发生脑脓肿]

[Cerebral abscess during a severe form of Salmonella typhimurium bacteremia in an immunocompetent patient].

作者信息

Broux C, Santré C, Sirodot M, Allantaz F, Genin G, Bru J P

机构信息

Service de Réanimation polyvalente, Centre Hospitalier de la Région Annécienne, Annecy.

出版信息

Presse Med. 1998;27(19):909-10.

PMID:9767851
Abstract

BACKGROUND

Bacteremia rarely occurs in non-typhoid salmonella infections and the development of a brain abscess is exceptional.

CASE REPORT

An immunocompetent patient developed severe Salmonella typhimurium bacteremia leading to septic shock and acute respiratory distress and acute renal failure. A brain abscess, which was not present on the initial brain tomodensitometry, developed and totally regressed after antibiotic therapy.

DISCUSSION

We were unable to identify and factor favoring the development of salmonella bacteremia in this patient. There were no cerebral lesions on the initial brain tomodensitometry considered to be normal. To our knowledge, this is the first report of Salmonella typhimurium brain abscess in an immunocompetent subject.

摘要

背景

非伤寒沙门氏菌感染很少发生菌血症,脑脓肿的形成更是罕见。

病例报告

一名免疫功能正常的患者发生了严重的鼠伤寒沙门氏菌菌血症,导致感染性休克、急性呼吸窘迫和急性肾衰竭。最初脑部计算机断层扫描未发现脑脓肿,但在抗生素治疗后出现并完全消退。

讨论

我们无法确定该患者发生沙门氏菌菌血症的有利因素。最初的脑部计算机断层扫描显示脑部无病变,被认为是正常的。据我们所知,这是免疫功能正常的个体中鼠伤寒沙门氏菌脑脓肿的首例报告。

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Salmonella brain abscess in a patient on chronic azathioprine therapy for myasthenia gravis: report of an unusual case and review of literature in the postantibiotic era.慢性免疫抑制剂硫唑嘌呤治疗重症肌无力患者的沙门氏菌脑脓肿:报告一例不常见病例,并复习后抗生素时代的文献。
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