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[α干扰素和γ干扰素对从一名流行性神经病患者分离出的柯萨奇A9毒株增殖的抑制作用]

[Inhibition of the multiplication of a Coxsackie A9 strain isolated from a patient with epidemic neuropathy by the interferons alfa and gamma].

作者信息

Guzmán Tirado M G, Soler Nodarse M, Más Lago P, Morier Díaz L, Castillo Alvarez A, Resik Aguirre S, Alvarez M, Kouri Flores G

机构信息

Instituto de Medicina Tropical Pedro Kouri.

出版信息

Rev Cubana Med Trop. 1994;46(1):13-5.

PMID:9768226
Abstract

We present the results of the in vitro action of alpha and gamma interferons and of Intacglobin and Igegam against the 47/93/IPK (Coxsackie A9) strain isolated from the cerebrospinal fluid of a patient with epidemic neuropathy. The in vitro studies showed that the two interferons inhibited the replication of this agent; they also showed the presence of antibodies to it in the Intacglobin and Igegam. The results attained demonstrated that the use of these compounds could be effective for the treatment of this entity.

摘要

我们展示了α和γ干扰素以及Intacglobin和Igegam对从一名流行性神经病患者脑脊液中分离出的47/93/IPK(柯萨奇A9)菌株的体外作用结果。体外研究表明,这两种干扰素抑制了该病原体的复制;研究还显示Intacglobin和Igegam中存在针对它的抗体。所获得的结果表明,使用这些化合物可能对治疗该疾病有效。

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