Fadok V A, Henson P M
Department of Pediatrics, National Jewish Medical and Research Center, Denver, Colorado 80206, USA.
Curr Biol. 1998 Sep 24;8(19):R693-5. doi: 10.1016/s0960-9822(98)70438-5.
Cells that die by apoptosis need to be removed before lysis to preserve tissue integrity and function. Recent studies have identified components of the uptake machinery used by phagocytes, but much remains to be learnt, particularly about the recognition mechanisms and their coupling to the uptake machinery.
通过凋亡死亡的细胞在裂解前需要被清除,以维持组织的完整性和功能。最近的研究已经确定了吞噬细胞所使用的摄取机制的组成部分,但仍有许多有待了解,特别是关于识别机制以及它们与摄取机制的耦合。