Institute of Molecular Biosciences, Biophysics Division, University of Graz, NAWI Graz, Humboldtstr 50/III, Graz, 8010, Austria.
BioTechMed-Graz, Graz, 8010, Austria.
Membranes (Basel). 2015 May 6;5(2):180-96. doi: 10.3390/membranes5020180.
Despite the ubiquity of transbilayer asymmetry in natural cell membranes, the vast majority of existing research has utilized chemically well-defined symmetric liposomes, where the inner and outer bilayer leaflets have the same composition. Here, we review various aspects of asymmetry in nature and in model systems in anticipation for the next phase of model membrane studies.
尽管双层不对称性在天然细胞膜中普遍存在,但绝大多数现有的研究都利用了化学性质明确的对称脂质体,其中内层和外层双层具有相同的组成。在这里,我们综述了自然界和模型系统中不对称性的各个方面,以期为下一阶段的模型膜研究做好准备。