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原发性干燥综合征患者的龋齿和牙周状况

Caries and periodontal conditions in patients with primary Sjögren's syndrome.

作者信息

Ravald N, List T

机构信息

Specialist Centre Oral Rehabilitation, Linköping, Sweden.

出版信息

Swed Dent J. 1998;22(3):97-103.

PMID:9768457
Abstract

The present investigation was designed to study caries and periodontal conditions in a selected group of patients with primary Sjögren's syndrome (1oSS). Twenty-one patients, 20 females and 1 male aged 44-75 years (mean 64 years), with recently diagnosed 1oSS constituted the study population. As a control group, 21 patients matched according to sex and age were randomly selected from patients at one clinic in the Public Dental Service. Clinical examinations including registrations of dental caries, restorations, and periodontal conditions were performed. Unstimulated and stimulated salivary secretion rates were recorded. The 1oSS group had a mean number of 16.4 +/- 8.9 and the control group 17.1 +/- 8.4 natural teeth. The 1oSS patients had significantly more DF crown surfaces (63 +/- 25.8 vs 43 +/- 21.3) and more inactive root caries (4.4 +/- 5.4 vs 0.5 +/- 0.9) than did the control patients. No significant differences were found between the groups in the periodontal conditions. The mean value of the unstimulated salivary secretion rate was 0.09 +/- 0.16 ml/15 min in the 1oSS group and 3.33 +/- 2.81 ml/15 min in the control group. The stimulated secretion rate was 0.16 +/- 0.15 ml/min and 1.47 +/- 0.64 ml/min respectively. This study confirms results from other studies that patients with 1oSS face a high risk of developing both coronal and root caries due to xerostomia. The periodontal conditions are similar to those found in patient groups in general dentistry.

摘要

本研究旨在调查一组原发性干燥综合征(pSS)患者的龋病和牙周状况。研究对象为21例患者,其中20例女性,1例男性,年龄44 - 75岁(平均64岁),均为近期诊断为pSS的患者。作为对照组,从公共牙科服务机构的一个诊所中随机选取21例年龄和性别匹配的患者。进行了包括龋齿、修复体和牙周状况登记的临床检查。记录了非刺激性和刺激性唾液分泌率。pSS组平均天然牙数为16.4±8.9颗,对照组为17.1±8.4颗。pSS患者的DF冠面明显多于对照组(63±25.8 vs 43±21.3),静止性根龋也更多(4.4±5.4 vs 0.5±0.9)。两组在牙周状况方面未发现显著差异。pSS组非刺激性唾液分泌率的平均值为0.09±0.16 ml/15分钟,对照组为3.33±2.81 ml/15分钟。刺激性分泌率分别为0.16±0.15 ml/分钟和1.47±0.64 ml/分钟。本研究证实了其他研究的结果,即pSS患者由于口干症面临发生冠龋和根龋的高风险。牙周状况与普通牙科患者群体中的情况相似。

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Diagnostics (Basel). 2023 Apr 12;13(8):1401. doi: 10.3390/diagnostics13081401.
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Expression of ICOS in the salivary glands of patients with primary Sjogren's syndrome and its molecular mechanism.原发性干燥综合征患者唾液腺中 ICOS 的表达及其分子机制。
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Next-generation sequencing of whole saliva from patients with primary Sjögren's syndrome and non-Sjögren's sicca reveals comparable salivary microbiota.
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Dental implants in Sjögren's syndrome patients: A systematic review.干燥综合征患者的牙种植体:一项系统评价。
PLoS One. 2017 Dec 14;12(12):e0189507. doi: 10.1371/journal.pone.0189507. eCollection 2017.
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