Neri M, Rubichi S, DeVreese L P, Roth M, Cipolli C
Chair of Geriatrics, Medical School, University of Modena, Italy.
Dement Geriatr Cogn Disord. 1998 Nov-Dec;9(6):339-46. doi: 10.1159/000017086.
The sensitivity and specificity of the two forms of the CAMDEX interview for dementia diagnosis were assessed in a 1-year follow-up study. At the beginning of the study, 60 patients (22 males and 38 females) who met DSM-IV criteria for dementia and 60 matched controls (15 males and 45 females), were administered the short form of the CAMDEX (short CAMDEX) 3 months after the full one (full CAMDEX). At the follow-up, all patients were administered both the full and short CAMDEX (again with a 3-month interval), whereas controls were administered either CAMDEX form (in any case, at a 12-month interval from initial testing). Upon initial testing, the sensitivity of the full CAMCOG proved to be significantly higher than that of the short CAMCOG, while the opposite trend was observed for specificity, that is the sensitivity of the full Organicity was lower than that of the short Organicity, with specificity remaining equal in the two forms. Upon follow-up, the specificity and sensitivity levels of the two forms did not significantly differ for the CAMCOG and Organicity indices. Moreover, in detecting mildly demented patients, the full CAMCOG proved to be more accurate than the short one, while the opposite trend was observed for Organicity. Among the dementia subjects, significant correlations were found between the homologous indices of the two forms for both test sessions. On the whole, the short CAMDEX appears to maintain most of the psychometric properties of the full version and therefore the two CAMDEX forms can be considered to be interchangeable.
在一项为期1年的随访研究中，对用于痴呆诊断的两种形式的CAMDEX访谈的敏感性和特异性进行了评估。研究开始时，60名符合DSM-IV痴呆标准的患者（22名男性和38名女性）以及60名匹配的对照者（15名男性和45名女性），在完成完整形式的CAMDEX（完整CAMDEX）3个月后接受了简短形式的CAMDEX（简短CAMDEX）。在随访时，所有患者都接受了完整和简短的CAMDEX（同样间隔3个月），而对照者则接受了任意一种CAMDEX形式（无论如何，与初始测试间隔12个月）。在初始测试时，完整CAMCOG的敏感性被证明显著高于简短CAMCOG，而特异性则呈现相反趋势，即完整器质性部分的敏感性低于简短器质性部分，两种形式的特异性保持相等。在随访时，CAMCOG和器质性部分两种形式的特异性和敏感性水平没有显著差异。此外，在检测轻度痴呆患者时，完整CAMCOG被证明比简短的更准确，而器质性部分则呈现相反趋势。在痴呆受试者中，两个测试阶段两种形式的同源指标之间存在显著相关性。总体而言，简短CAMDEX似乎保留了完整版本的大部分心理测量特性，因此可以认为两种CAMDEX形式是可互换的。
