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[与结肠癌相关的福尼尔坏疽]

[Fournier's gangrene associated with carcinoma of the colon].

作者信息

Veljković R, Milosević P, Stojanović S

机构信息

Institut za hirurgiju, Medicinski fakultet, Novi Sad.

出版信息

Med Pregl. 1998 Jul-Aug;51(7-8):351-4.

PMID:9769671
Abstract

BACKGROUND

A case of Fournier's gangrene associated with colon carcinoma was reported. Fournier's gangrene is a progressive soft tissue infection of the perineal and scrotal region.

CASE REPORT

A 50-year-old man was transferred to our hospital with clinical signs of septic shock and necrotizing soft tissue infection, of the scrotal and perianal regions. Local examination revealed a communication between rectum and left ishioanal fossa, many openings in the skin with purulent discharge and crepitus. After resuscitation the patient underwent emergent operation. Surgical debridements were performed. The wounds healed well with good granulation tissue.

DISCUSSION

The majority of patients with Fournier's gangrene are immunocompromised. Malignant disease, obesity, diabetes mellitus and peripheral vascular disease have been cited as the main predisposing factors. The origin of this synergic infection is in alimentary and urinary tract. As a rule, penis, testes, bladder and rectum are spared. Conventional treatment includes repeated surgical debridement, special antibiotic regimen to cover both, aerobes and anaerobes, and intensive care treatment. Despite optimal medical and surgical management the mortality rate in Fournier's gangrene still remains high.

摘要

背景

报告了一例与结肠癌相关的福尼尔坏疽病例。福尼尔坏疽是一种会阴部和阴囊区域的进行性软组织感染。

病例报告

一名50岁男性因出现感染性休克及阴囊和肛周区域坏死性软组织感染的临床症状被转诊至我院。局部检查发现直肠与左侧坐骨直肠窝相通,皮肤上有多处开口并有脓性分泌物及捻发音。复苏后患者接受了急诊手术。进行了手术清创。伤口愈合良好,有良好的肉芽组织。

讨论

大多数福尼尔坏疽患者存在免疫功能低下。恶性疾病、肥胖、糖尿病和外周血管疾病被认为是主要的诱发因素。这种协同感染起源于消化道和泌尿道。通常,阴茎、睾丸、膀胱和直肠不受影响。常规治疗包括反复手术清创、覆盖需氧菌和厌氧菌的特殊抗生素方案以及重症监护治疗。尽管进行了最佳的药物和手术治疗,福尼尔坏疽的死亡率仍然很高。

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