Mosnier I, Bouccara D, Atassi-Dumont M, Sterkers O
Hôpital Beaujon, Faculté Xavier Bichat, Université Paris 7, Service d'ORL, Clichy, France.
Rev Laryngol Otol Rhinol (Bord). 1998;119(2):119-28.
In this report of a retrospective study of 144 cases of idiopathic sudden hearing loss, two important prognostic indicators appear: the elapsed time since the onset of symptoms and the degree of hearing loss. According to these indicators, the authors define three group of patients with a recovery rate of 65%: patients with a threshold hearing level of less than 40 dB, treated within two months of the onset of their hearing loss, patients with a threshold hearing level between 40 and 70 dB treated within one month and patients with a threshold hearing level of more than 70 dB treated within 7 days. Patients with a threshold hearing level of more than 70 dB, treated between 7 and 30 days, have only a partial recovery in 40%. The evaluation of efficacy of various treatment demonstrates a slight improvement of the hearing loss using steroids associated to vasodilatators, even if no significant difference is found between the different therapies. The normovolemic hemodilution and the treatment included mannitol seem to be ineffectual.
在这份对144例特发性突发性感音神经性听力损失病例的回顾性研究报告中，出现了两个重要的预后指标：症状出现后的时间间隔以及听力损失程度。根据这些指标，作者将患者分为三组，其恢复率为65%：听力阈值水平低于40分贝且在听力损失发作后两个月内接受治疗的患者；听力阈值水平在40至70分贝之间且在一个月内接受治疗的患者；听力阈值水平高于70分贝且在7天内接受治疗的患者。听力阈值水平高于70分贝且在7至30天内接受治疗的患者，仅有40%能部分恢复。对各种治疗效果的评估表明，使用类固醇联合血管扩张剂可使听力损失略有改善，尽管不同疗法之间未发现显著差异。等容血液稀释以及包含甘露醇的治疗似乎无效。
