Tunali T, Yarat A, Yanardağ R, Ozçelík F, Ozsoy O, Ergenekon G, Emeklí N
Department of Biochemistry, Faculty of Dentistry, Marmara University, Nişantaşi, Turkey.
Pharmazie. 1998 Sep;53(9):638-40.
Chard (Beta vulgaris L. var. cicla) is one of the plants used as hypoglycaemic agent by diabetics in Turkey and it has been reported to reduce blood glucose. The purpose of this study was to investigate the effect of feeding chard on diabetes induced impairments in rat skins. Uncontrolled induced diabetes caused significant increases in nonenzymatic glycosylation of skin proteins, lipid peroxidation and blood glucose. Administration of chard extract inhibited these effects except the increase in lipid peroxidation. SDS-polyacrylamide gel electrophoresis revealed no significant differences in any protein bands between any of the groups. The data indicate that the use of chard may be effective in preventing or at least retarding the development of some diabetic complications.
叶用甜菜（Beta vulgaris L. var. cicla）是土耳其糖尿病患者用作降血糖剂的植物之一，据报道它能降低血糖。本研究的目的是调查喂食叶用甜菜对大鼠皮肤糖尿病诱发损伤的影响。未控制的诱导糖尿病导致皮肤蛋白质非酶糖基化、脂质过氧化和血糖显著增加。叶用甜菜提取物的给药抑制了这些影响，但脂质过氧化增加除外。SDS-聚丙烯酰胺凝胶电泳显示各实验组之间任何蛋白质条带均无显著差异。数据表明，使用叶用甜菜可能对预防或至少延缓某些糖尿病并发症的发展有效。
