Lebrun C, Girard P, Paquis P, Marcy P Y, Chatel M, Frénay M
Service de Neurologie, Hôpital Pasteur, Nice.
Rev Neurol (Paris). 1998 Apr;154(3):246-9.
Germinoma is the most frequent type of intracranial germ-cell tumor initial presentation is usually acute intracranial hypertension. MRI investigations are non-specific. Most of the time, only stereotactic surgery is performed before treatment. Metastases are rare but germ cells can disseminate both by infiltration and via ventricular and subarachnoid pathways. Abdominal and pelvic metastases occur in 10 p. 100 of patients who have received ventriculosomatic shunting. Since germinoma is well known to be a very radiosensitive tumor, patients are usually given radiation therapy. Chemotherapy seems to be an interesting alternative treatment.
生殖细胞瘤是最常见的颅内生殖细胞肿瘤类型，其初始表现通常为急性颅内高压。磁共振成像（MRI）检查无特异性。大多数情况下，治疗前仅进行立体定向手术。转移罕见，但生殖细胞可通过浸润以及经脑室和蛛网膜下腔途径播散。在接受脑室体分流术的患者中，10%会出现腹部和盆腔转移。由于众所周知生殖细胞瘤是一种对放疗非常敏感的肿瘤，患者通常接受放射治疗。化疗似乎是一种有趣的替代治疗方法。
