Patra G, Vaissaire J, Weber-Levy M, Le Doujet C, Mock M
Unité des Toxines et Pathogénie Bactériennes (URA CNRS 1858), Institut Pasteur, 75724 Paris, France.
J Clin Microbiol. 1998 Nov;36(11):3412-4. doi: 10.1128/JCM.36.11.3412-3414.1998.
Outbreaks of anthrax zoonose occurred in two regions of France in 1997. Ninety-four animals died, and there were three nonfatal cases in humans. The diagnosis of anthrax was rapidly confirmed by bacteriological and molecular biological methods. The strains of Bacillus anthracis in animal and soil samples were identified by a multiplex PCR assay. They all belonged to the variable-number tandem repeat (VNTR) group (VNTR)3. A penicillin-resistant strain was detected. Nonvirulent bacilli related to B. anthracis, of all VNTR types, were also found in the soil.
1997年，法国两个地区爆发了炭疽人畜共患病。94只动物死亡，3例人类感染为非致命病例。通过细菌学和分子生物学方法迅速确诊为炭疽。采用多重PCR检测法对动物和土壤样本中的炭疽芽孢杆菌菌株进行鉴定。它们均属于可变数目串联重复序列（VNTR）组（VNTR）3。检测到一株耐青霉素菌株。在土壤中还发现了与炭疽芽孢杆菌相关的所有VNTR类型的无毒杆菌。
