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[乳头状纤维弹性瘤。年轻患者中风的罕见病因]

[Papillary fibroelastoma. A rare etiology of strokes in young patients].

作者信息

Bailbé M, Coisne D, Babin P, Corbi P, Menu P, Rosier M P, Couderq C, Pouget Abadie J F, Gil R, Neau J P

机构信息

Service de neurologie, hôpital Jean-Bernard, CHU La Milétrie, Poitiers.

出版信息

Rev Med Interne. 1998 Feb;19(2):119-22. doi: 10.1016/s0248-8663(97)83421-2.

Abstract

BACKGROUND

The papillary fibroelastomas are cardiac lesions, which typically occur on the cardiac valves, but rarely on the endocardium. The incidence of these benign primitive tumors varies from 0.002 to 0.33% and increases with advancing age.

METHODS

We report two cases of stroke, one in a 31-year-old man and the other in a 48-year-old woman, both admitted to the same stroke center.

RESULTS

The diagnostic studies were normal in these two patients, except for the echocardiography. The first showed an echogenic mass on the mitral valve on transthoracic echocardiography (TTE), confirmed by the transesophageal echocardiography (TEE). The second demonstrated a mass on the sigmoid aortic valve on TEE, but the TTE was normal. For these two patients, a surgical excision was carried out and pathologic examination concluded to a papillary fibroelastoma. After surgery, no recurrence was observed.

CONCLUSIONS

The papillary fibroelastomas are usually asymptomatic and easily detected by TEE. However, it can be revealed by stroke, myocardial infarction and lower limbs ischemia. These cardiac tumors should be surgically removed, since their complete excision remains the only means of avoiding a recurrence of embolism.

摘要

背景

乳头状纤维弹性瘤是心脏病变,通常发生在心脏瓣膜,但很少发生在心内膜。这些良性原发性肿瘤的发病率在0.002%至0.33%之间,且随年龄增长而增加。

方法

我们报告两例中风病例,一例为31岁男性,另一例为48岁女性,均入住同一中风中心。

结果

这两名患者除超声心动图外,其他诊断检查均正常。第一例经胸超声心动图(TTE)显示二尖瓣上有一个回声团块,经食管超声心动图(TEE)证实。第二例TEE显示乙状主动脉瓣上有一个团块,但TTE正常。对于这两名患者,均进行了手术切除,病理检查结果为乳头状纤维弹性瘤。术后未观察到复发。

结论

乳头状纤维弹性瘤通常无症状,TEE易于检测到。然而,它可表现为中风、心肌梗死和下肢缺血。这些心脏肿瘤应手术切除,因为完整切除仍然是避免栓塞复发的唯一方法。

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