Ruske D R, Glassford N, Costello S, Stewart I A
Department of Otolaryngology, Dunedin Hospital, New Zealand.
J Laryngol Otol. 1998 Jul;112(7):670-2. doi: 10.1017/s0022215100141416.
Laryngeal rhabdomyosarcoma is a rare disease. Only nine of these tumours have been adequately described in world literature in the adult population. Adult patients with laryngeal rhabdomyosarcoma often present at a later stage than other laryngeal tumours, including squamous cell carcinoma. Diagnosis is made by identification of cross-striations histochemically or cytoplasmic myoglobin by immunohistological methods. We present a 66-year-old woman with pleomorphic rhabdomyosarcoma of her larynx. This is the first female in the adult age group to be presented. Surgical treatment with adjuvant radiotherapy is currently the treatment of choice for this disease. We provide a review of the literature on laryngeal rhabdomyosarcoma, including presentation, pathology and management of this rare disease.
喉横纹肌肉瘤是一种罕见疾病。世界文献中仅对9例成人喉横纹肌肉瘤进行了充分描述。与包括鳞状细胞癌在内的其他喉部肿瘤相比，成年喉横纹肌肉瘤患者就诊时往往处于疾病晚期。诊断需通过组织化学方法识别横纹或免疫组织学方法检测细胞质肌红蛋白来进行。我们报告了一名66岁患有喉部多形性横纹肌肉瘤的女性。这是成年年龄组中报道的首例女性患者。手术治疗联合辅助放疗是目前该病的首选治疗方法。我们对喉横纹肌肉瘤的文献进行了综述，包括这种罕见疾病的临床表现、病理及治疗。
