Dahlén G, Rosling B
Int Dent J. 1998 Apr;48(2):104-10. doi: 10.1111/j.1875-595x.1998.tb00468.x.
The aim of the present study was to evaluate whether the presence of A. actinomycetemcomitans, P. gingivalis and P. intermedia, as revealed by culture technique, could discriminate between three distinct adult patient groups, those: with recurrent periodontal disease, with cured periodontal disease or who were periodontally healthy. Forty one patients previously treated for advanced periodontitis were divided into recurrent or cured groups, with a third periodontally healthy reference group. All subjects were sampled for the three bacterial strains under scrutiny. Although all three micro-organisms were found significantly more often in diseased sites, it was concluded that a sample positive for all three may indicate a false record of disease activity. However, a sample negative for the three bacteria strongly indicates an absence of disease activity.
本研究的目的是评估通过培养技术检测到的伴放线放线杆菌、牙龈卟啉单胞菌和中间普氏菌的存在，是否能够区分三组不同的成年患者：患有复发性牙周病的患者、已治愈牙周病的患者或牙周健康的患者。41名先前接受过重度牙周炎治疗的患者被分为复发组或治愈组，另有第三组作为牙周健康的参照组。对所有受试者进行取样，以检测这三种受监测的细菌菌株。尽管在患病部位发现这三种微生物的频率显著更高，但得出的结论是，三种微生物检测结果均为阳性的样本可能表明疾病活动记录有误。然而，三种细菌检测结果均为阴性的样本则强烈表明不存在疾病活动。
