Washburn R G
Section on Infectious Diseases, Bowman Gray School of Medicine of Wake Forest University, Winston-Salem, North Carolina, USA.
Curr Clin Top Infect Dis. 1998;18:60-74.
Noninvasive fungal sinusitis usually occurs in individuals with a poorly draining maxillary sinus. The infection can be cured by surgical removal of the hyphal mass. In contrast, allergic fungal sinusitis is an upper respiratory disease with an immunopathology similar to that of allergic bronchopulmonary aspergillosis. Surgical debridement and therapy with topical or systemic steroids are recommended. Acute and chronic invasive fungal sinusitis are extremely serious infections requiring aggressive therapy, including extensive surgical debridement and appropriate antifungal chemotherapy. For acute invasive fungal sinusitis in the neutropenic host, survival depends chiefly on bone marrow recovery.
非侵袭性真菌性鼻窦炎通常发生在上颌窦引流不畅的个体中。通过手术切除菌丝团可治愈感染。相比之下，变应性真菌性鼻窦炎是一种上呼吸道疾病，其免疫病理学与变应性支气管肺曲霉病相似。建议进行手术清创并使用局部或全身类固醇进行治疗。急性和慢性侵袭性真菌性鼻窦炎是极其严重的感染，需要积极治疗，包括广泛的手术清创和适当的抗真菌化疗。对于中性粒细胞减少宿主中的急性侵袭性真菌性鼻窦炎，生存主要取决于骨髓恢复。
