Bouchaud O, Longuet C, Coulaud J P
Consultation de médecine tropicale Hôpital Bichat-Claude Bernard, Paris.
Rev Prat. 1998 Feb 1;48(3):279-86.
Malaria, occurring in 1 to 2% of unprotected travellers to sub-Saharian Africa, remains a real risk because of its potential severity. In Asia or Latin America, the risk appears to be much lower, and in some cases, prevention can be limited to measures to avoid mosquito bites. Chemoprophylaxis by chloroquine-proguanil, mefloquine or, less frequently cyclines, is efficacious but poor compliance and frequent adverse events limits its interest. No regimen is totally effective and malaria must be considered in any traveller coming back from an endemic area with fever, even still receiving an appropriate prophylaxis.
疟疾在前往撒哈拉以南非洲且未采取防护措施的旅行者中发病率为1%至2%，因其潜在的严重性，仍然是一个切实存在的风险。在亚洲或拉丁美洲，风险似乎要低得多，在某些情况下，预防措施可仅限于避免蚊虫叮咬。使用氯喹-氯胍、甲氟喹或较少使用的四环素进行化学预防是有效的，但依从性差和频繁的不良事件限制了其应用价值。没有一种方案是完全有效的，对于任何从疟疾流行地区回来且发烧的旅行者，即使仍在接受适当的预防措施，也必须考虑到疟疾的可能性。
