Goulet O
Gastroentérologie et nutrition pédiatriques Hôpital Necker-Enfants Malades, Paris.
Rev Prat. 1998 Feb 15;48(4):403-9.
Pediatric Crohn's disease is a severe disease with digestive and extra-digestive manifestations. Growth retardation is a common feature. Diagnosis is based on endoscopy and histology with evidence of granulomas. Remission can be achieved by using anti-inflammatory treatment or continuous enteral feeding. Course of the disease is marked by relapse with extension. Surgery is limited in children. Ulcerative colitis is limited on rectum and colon and includes also extra-digestive manifestations. Bloody diarrhoea with abdominal pain is characteristic. Diagnosis is based on endoscopy and histology. Treatment depends on the severity of the disease but can include rapidly colectomy for persistent severe bloody diarrhoea.
小儿克罗恩病是一种伴有消化系统和消化系统外表现的严重疾病。生长发育迟缓是其常见特征。诊断基于内镜检查和组织学检查,并伴有肉芽肿证据。使用抗炎治疗或持续肠内喂养可实现缓解。疾病病程以复发并扩展为特征。儿童手术受限。溃疡性结肠炎局限于直肠和结肠,也包括消化系统外表现。伴有腹痛的血性腹泻是其特征。诊断基于内镜检查和组织学检查。治疗取决于疾病的严重程度,但对于持续性严重血性腹泻可能包括紧急结肠切除术。