Taylor C E, Osman H K, Turner A J, Flood T J, Abinun M, Crooks B, Cant A J
Newcastle Public Health Laboratory, Newcastle General Hospital, Newcastle upon Tyne.
Commun Dis Public Health. 1998 Sep;1(3):202-3.
Respiratory syncytial virus and parainfluenza virus infection carry a poor prognosis in severe combined immunodeficiency (SCID), particularly if the viral load is high. Patients with high viral load develop severe pneumonitis at engraftment which may possibly be modulated by immunotherapy, including high dose nebulised corticosteroids. Further work is required to develop effective treatment for this severe condition.
呼吸道合胞病毒和副流感病毒感染在重症联合免疫缺陷(SCID)中预后较差,尤其是病毒载量高时。病毒载量高的患者在移植时会发生严重肺炎,这可能通过免疫疗法进行调节,包括高剂量雾化糖皮质激素。需要进一步开展工作来开发针对这种严重病症的有效治疗方法。