[氟烷在体外长时间作用下肝脏线粒体的能量参数]
[The energy parameters of the liver mitochondria under the prolonged action of halothane in vitro].
作者信息
Ovchinnikov I V, Kim N P, Akhmerov R N, Ishankulova G F
机构信息
Laboratory of Biochemistry, Uzbekistan Republic Ministry of Public Health, Tashkent.
出版信息
Eksp Klin Farmakol. 1998 Jul-Aug;61(4):38-40.
PMID:9783107
Abstract
The effect of 10-, 30-, 60-, 90-, and 120-min exposure to halotane vapors on the energy parameters of mitochondria of the liver of albino rats was studied in in vitro experiments. In long-term contact of the mitochondria with halotane the respiratory and phosphorylation function of the mitochondria in oxidation of PAD- and NAD-dependent substrates was disturbed.
摘要
在体外实验中，研究了将白化大鼠肝脏线粒体暴露于氟烷蒸汽10分钟、30分钟、60分钟、90分钟和120分钟对其能量参数的影响。线粒体与氟烷长期接触会干扰其在氧化PAD和NAD依赖性底物时的呼吸和磷酸化功能。
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