完整动物及单侧肾切除术后大鼠肾脏中的阿司匹林损伤。

J Pathol. 1976 Sep;120(1):43-8. doi: 10.1002/path.1711200106.

Aspirin caused epithelial hyperplasia, papillary necrosis with calcification and cortical changes in the rat kidney. After unilateral nephrectomy the lesions appeared more rapidly and were more severe. In the electron microscope the earliest changes were observed in the interstitial cells.

阿司匹林可导致大鼠肾脏出现上皮增生、伴有钙化的乳头坏死以及皮质改变。单侧肾切除术后，这些病变出现得更快且更严重。在电子显微镜下，最早的变化出现在间质细胞中。