I型（胰岛素依赖型）糖尿病儿童及青少年的胰腺大小

Size of pancreas in children and adolescents with type I (insulin-dependent) diabetes.

作者信息

Altobelli E, Blasetti A, Verrotti A, Di Giandomenico V, Bonomo L, Chiarelli F

机构信息

Epidemiological Research Centre, Faculty of Medicine, University of L'Aquila, Coppito, Italy.

出版信息

J Clin Ultrasound. 1998 Oct;26(8):391-5. doi: 10.1002/(sici)1097-0096(199810)26:8<391::aid-jcu3>3.0.co;2-d.

DOI:10.1002/(sici)1097-0096(199810)26:8<391::aid-jcu3>3.0.co;2-d

PMID:9783245

Abstract

PURPOSE

The aim of this study was to evaluate the influence of insulin-dependent diabetes mellitus (IDDM) on the size of the pancreas in children.

METHODS

Pancreas size was evaluated sonographically in a group of 60 diabetic children and adolescents, aged 3-15 years, and 60 sex- and age-matched healthy controls.

RESULTS

A significant reduction in pancreatic area and other parameters was found in diabetic patients particularly in children aged 8-12 and 13-15 years. The pancreas was larger in children 3-7 years old who had had IDDM for 2 years of less (mean size, 8.61 cm2) than in children 8-12 and 13-15 years old who had had IDDM for more than 5 years (mean size, 8.06 and 8.40 cm2, respectively). An inverse correlation between area of the pancreas and duration of IDDM was seen in all age groups (p < 0.05).

CONCLUSIONS

Diabetes affects the growth of the pancreas in children with IDDM. Sonography can be used to noninvasively evaluate the influence of the disease on pancreas size.

摘要

目的

本研究旨在评估胰岛素依赖型糖尿病（IDDM）对儿童胰腺大小的影响。

方法

对一组60名年龄在3至15岁的糖尿病儿童和青少年以及60名年龄和性别匹配的健康对照者进行胰腺大小的超声评估。

结果

糖尿病患者的胰腺面积和其他参数显著减小，尤其是8至12岁和13至15岁的儿童。病程小于2年的3至7岁IDDM儿童的胰腺（平均大小为8.61平方厘米）比病程超过5年的8至12岁和13至15岁儿童的胰腺更大（平均大小分别为8.06平方厘米和8.40平方厘米）。在所有年龄组中，胰腺面积与IDDM病程呈负相关（p < 0.05）。