Gryglewska B, Grodzicki T, Kocemba J
Department of Gerontology and Family Medicine, Jagiellonian University School of Medicine, Cracow, Poland.
J Hum Hypertens. 1998 Sep;12(9):645-7. doi: 10.1038/sj.jhh.1000684.
The aim of presented analysis was to determine the relationship between blood pressure (BP) and different indices of obesity in the elderly free-living population.
In 317 inhabitants of the randomly chosen area of Cracow (70 years old and older) who could come to the out-patient clinic for an interview, BP, weight and height were taken. Body mass index (BMI) was used to classify the population into lean (BMI < 25 kg/m2), overweight (25 < or = BMI < 30 kg/m2) and obese (BMI > or = 30 kg/m2) subjects. In order to separate the effect of adipose tissue and lean body mass, weight of total adipose tissue (AT) and lean body mass (LBM) were calculated according to the anthropometric CT-calibrated equations.
Obese patients had a significantly higher systolic BP (SBP) when compared with lean subjects (respectively SBP [mm Hg] 175.7 +/- 27.5 vs 161.8 +/- 21.8), and higher diastolic BP (DBP) [mm Hg] in comparison with both other groups (obese: 93.7 +/- 12.4 vs lean: 85.34 +/- 10.6, overweight: 87.15 +/- 12.73). The relationship between systolic and diastolic BP, and weight (respectively for SBP: r = 0.256, DBP: r = 0.216), BMI (SBP: r = 0.261, DBP: r = 0.216) and AT (SBP r = 0.269, DBP r = 0.22, P < 0.01) was found only in women but not in men.
Our results suggest that in the elderly the importance of obesity in the pathogenesis of hypertension depends partially on gender and it may be essential in women but not in men.
本分析的目的是确定老年自由生活人群的血压（BP）与不同肥胖指标之间的关系。
在随机选择的克拉科夫地区317名居民（年龄在70岁及以上）中，这些居民能够前来门诊接受访谈，测量了他们的血压、体重和身高。体重指数（BMI）用于将人群分为瘦（BMI<25kg/m²）、超重（25≤BMI<30kg/m²）和肥胖（BMI≥30kg/m²）受试者。为了区分脂肪组织和瘦体重的影响，根据人体测量学CT校准方程计算了总脂肪组织（AT）和瘦体重（LBM）的重量。
与瘦受试者相比，肥胖患者的收缩压（SBP）显著更高（SBP[mmHg]分别为175.7±27.5对161.8±21.8），与其他两组相比，舒张压（DBP）[mmHg]也更高（肥胖组：93.7±12.4对瘦组：85.34±10.6，超重组：87.15±12.73）。收缩压和舒张压与体重（SBP：r=0.256，DBP：r=0.216）、BMI（SBP：r=0.261，DBP：r=0.216）和AT（SBP r=0.269，DBP r=0.22，P<0.01）之间的关系仅在女性中发现，而在男性中未发现。
我们的结果表明，在老年人中，肥胖在高血压发病机制中的重要性部分取决于性别，对女性可能至关重要，而对男性则不然。
