Liam C K, Lim K H, Srinivas P, Poi P J
Department of Medicine, University Hospital, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Int J Tuberc Lung Dis. 1998 Oct;2(10):818-23.
University Hospital, Kuala Lumpur, Malaysia.
To determine the incidence of hypercalcaemia in Malaysian patients with newly diagnosed tuberculosis (TB) before the commencement of antituberculosis treatment.
A prospective study of consecutive patients with newly diagnosed bacteriologically and/or histologically proven tuberculosis in our institution from September 1994 to March 1996.
Of a total of 120 patients (67 males, 53 females), 68 had pulmonary TB, nine had pulmonary and pleural TB, 18 had pleural TB without chest radiograph evidence of lung involvement, 16 had various other forms of extra-pulmonary TB and nine had disseminated TB. The mean age of the patients was 44.3 (+/-18.0) years. The mean albumin-adjusted serum calcium concentration was 2.53 (+/-0.22) mmol/l. Hypercalcaemia was present in 27.5% of the patients, but only 12% of these patients showed symptoms of hypercalcaemia. The type of TB and, in the case of pulmonary TB, the radiographic extent of lung involvement, had no effect on the serum calcium level.
Hypercalcaemia is not uncommon among Malaysian patients with newly diagnosed TB, but it is rarely symptomatic.
马来西亚吉隆坡大学医院。
确定马来西亚新诊断肺结核（TB）患者在开始抗结核治疗前高钙血症的发生率。
对1994年9月至1996年3月在我们机构新诊断的经细菌学和/或组织学证实的肺结核患者进行前瞻性研究。
总共120例患者（67例男性，53例女性），其中68例患有肺结核，9例患有肺结核和胸膜炎，18例患有胸膜炎但胸部X线片无肺部受累证据，16例患有其他各种肺外结核形式，9例患有播散性结核。患者的平均年龄为44.3（±18.0）岁。白蛋白校正后的血清钙平均浓度为2.53（±0.22）mmol/L。27.5%的患者存在高钙血症，但这些患者中只有12%出现高钙血症症状。结核类型以及肺结核患者肺部受累的X线范围对血清钙水平无影响。
高钙血症在马来西亚新诊断的肺结核患者中并不少见，但很少有症状。
