Ohtsu H, Tanaka R, Matsunaga S
Osaka University of Pharmaceutical Sciences, 4-20-1 Nasahara, Takatsuki, Osaka 569-1094, Japan.
J Nat Prod. 1998 Oct;61(10):1307-9. doi: 10.1021/np980159d.
Three new abietane-type diterpenes, 7alpha,15-dihydroxyabieta-8,11, 13-trien-18-al (1); 15,18-dihydroxyabieta-8,11,13-trien-7-one (2); and 18-nor-4,15-dihydroxyabieta-8,11,13-trien-7-one (3), were isolated from the cones of Larix kaempferi, together with three known diterpenes, abieta-8,11,13-trien-18-yl succinate, 16-nor-15-oxoabieta-8,11,13-trien-18-oic acid, and 7beta-hydroxyabieta-8,11,13-trien-18-oic acid. The structures of 1-3 were determined on the basis of chemical and spectral evidence.
从日本落叶松球果中分离出三种新的枞酸型二萜，即7α,15 - 二羟基枞-8,11,13 - 三烯-18 - 醛（1）；15,18 - 二羟基枞-8,11,13 - 三烯-7 - 酮（2）；以及18 - 降-4,15 - 二羟基枞-8,11,13 - 三烯-7 - 酮（3），同时还分离出三种已知二萜，枞-8,11,13 - 三烯-18 - 基琥珀酸酯、16 - 降-15 - 氧代枞-8,11,13 - 三烯-18 - 酸和7β - 羟基枞-8,11,13 - 三烯-18 - 酸。根据化学和光谱证据确定了1 - 3的结构。
