Kapur S, Mittal A
Institute of Pathology (ICMR), New Delhi.
Indian J Med Res. 1998 Aug;108:45-50.
The concurrence of human immunodeficiency virus (HIV) infection with hepatitis B virus (HBV) and syphilis and the trend that these infections have followed in blood donors during the last eight years from 1989 to 1997 were studied at a Zonal Blood Testing Centre in New Delhi. Overall, HIV was positive in 0.068 per cent blood donors in this period. A significant rise was found in HIV infection (particularly in a small subgroup of voluntary donors) after 1995 and in VDRL reactivity after 1993. However, no significant increase was found in hepatitis B surface antigen (HBsAg) positivity. HIV seroprevalence in replacement donors, which represents the low risk general population, increased gradually from 0 in 1991 to an average of 0.060 per cent in 1997. HbsAg and VDRL reactivity was present in 12.2 and 11.8 per cent of HIV positive cases while it was present in 1.2 and 2.3 per cent of HIV negative cases respectively. HBsAg was found 10.4 times and VDRL reactivity 5.9 times more often in HIV positive donors as compared to HIV negative donors. Thus, HIV infection is likely to be more prevalent in communities with a high HBsAg positivity and VDRL reactivity.
在新德里的一个地区血液检测中心，研究了1989年至1997年这八年期间人类免疫缺陷病毒（HIV）感染与乙型肝炎病毒（HBV）及梅毒的并发情况，以及这些感染在献血者中的发展趋势。总体而言，在此期间0.068%的献血者HIV呈阳性。1995年后发现HIV感染（特别是在一小部分自愿献血者中）显著上升，1993年后VDRL反应性显著上升。然而，乙型肝炎表面抗原（HBsAg）阳性率未发现显著增加。替代献血者中的HIV血清流行率代表低风险普通人群，从1991年的0逐渐上升至1997年的平均0.060%。HBsAg和VDRL反应性在HIV阳性病例中分别占12.2%和11.8%，而在HIV阴性病例中分别占1.2%和2.3%。与HIV阴性献血者相比，HIV阳性献血者中HBsAg的发现率高10.4倍，VDRL反应性高5.9倍。因此，在HBsAg阳性率和VDRL反应性高的社区中，HIV感染可能更为普遍。
