Milne S T, Meek P D
Department of Emergency Medicine, University of Cincinnati, OH 45267-0769, USA.
Am J Emerg Med. 1998 Oct;16(6):603-8. doi: 10.1016/s0735-6757(98)90228-5.
Colchicine poisoning is an uncommon, but potentially life-threatening, toxicologic emergency. A case is reported of a 21-year-old woman who presented to the emergency department approximately 1 hour after ingesting 30 mg of colchicine in a suicide attempt. Her clinical course included gastrointestinal distress, metabolic acidosis, pancytopenia, hypotension, adult respiratory distress syndrome, rhabdomyolysis, and hypocalcemia. Despite aggressive medical management, the patient suffered a cardiac arrest and died 8 days after the ingestion. The clinical features of colchicine poisoning are highlighted and current therapeutic options are discussed.
秋水仙碱中毒是一种罕见但可能危及生命的中毒急症。本文报告了一例21岁女性病例，该患者在自杀企图中摄入30毫克秋水仙碱后约1小时被送往急诊科。她的临床过程包括胃肠道不适、代谢性酸中毒、全血细胞减少、低血压、成人呼吸窘迫综合征、横纹肌溶解和低钙血症。尽管进行了积极的医疗处理，但患者仍发生心脏骤停，并在摄入药物8天后死亡。文中强调了秋水仙碱中毒的临床特征，并讨论了当前的治疗选择。
