Buckner R L
Department of Psychology, Washington University, St. Louis, Missouri 63130, USA.
Hum Brain Mapp. 1998;6(5-6):373-7. doi: 10.1002/(SICI)1097-0193(1998)6:5/6<373::AID-HBM8>3.0.CO;2-P.
Event-related functional magnetic resonance imaging (ER-fMRI) methods are allowing a new spectrum of task designs to be explored with brain imaging techniques. Individual trial events can be presented rapidly, in randomly intermixed order, and the hemodynamic responses associated with individual trial events appreciated. The basis of ER-fMRI is that the hemodynamic response tracks neuronal activity on the order of seconds and, in many situations, summates over trials in a manner well predicted by a linear model--even for trials spaced as briefly as 2 sec apart. These properties are discussed, as well as certain basic characteristics of the hemodynamic response in the context of ER-fMRI.
事件相关功能磁共振成像（ER-fMRI）方法使得利用脑成像技术探索新的任务设计范围成为可能。单个试验事件可以快速呈现，以随机混合的顺序排列，并且可以识别与单个试验事件相关的血液动力学反应。ER-fMRI的基础是血液动力学反应在秒级水平上追踪神经元活动，并且在许多情况下，以线性模型能够很好预测的方式在试验中累加——即使对于间隔仅2秒的试验也是如此。本文将讨论这些特性，以及在ER-fMRI背景下血液动力学反应的某些基本特征。
