Chisholm C A, Heider A L, Kuller J A, von Allmen D, McMahon M J, Chescheir N C
Department of Obstetrics and Gynecology, University of North Carolina School of Medicine, Chapel Hill, USA.
Am J Perinatol. 1998 Aug;15(8):503-5. doi: 10.1055/s-2007-994074.
Sacrococcygeal teratoma is the most common fetal neoplasm, with an incidence of 1 in 40,000 births. Fetuses with this malformation are at risk for significant perinatal morbidity and mortality. We identified nine fetuses with sacrococcygeal teratomas that were diagnosed antenatally and managed at the University of North Carolina Hospitals over a 7-year period. We reviewed retrospectively the charts of mothers and infants and recorded data concerning perinatal and surgical management. Six infants survived the neonatal period. All infants diagnosed after 20 weeks' gestation survived. Fetal hydrops developed in three fetuses, all of whom died. Inadequate ventilation secondary to prematurity was a contributing factor in each lethal case. Diagnosis at an early gestational age, development of fetal hydrops, and premature delivery predicted a poor prognosis. When possible, we recommend that delivery be delayed to allow for fetal development. Stabilization of the infant should be attempted before resection of the teratoma.
骶尾部畸胎瘤是最常见的胎儿肿瘤，发病率为每40000例出生中有1例。患有这种畸形的胎儿有围产期显著发病和死亡的风险。我们确定了9例骶尾部畸胎瘤胎儿，这些胎儿在北卡罗来纳大学医院在7年期间进行了产前诊断和管理。我们回顾性地查阅了母亲和婴儿的病历，并记录了围产期和手术管理的数据。6例婴儿存活至新生儿期。所有在妊娠20周后诊断出的婴儿均存活。3例胎儿发生胎儿水肿，均死亡。早产导致的通气不足是每例致死病例的一个促成因素。孕早期诊断、胎儿水肿的发生和早产预示预后不良。可能的话，我们建议延迟分娩以促进胎儿发育。在切除畸胎瘤之前应尝试稳定婴儿状况。
