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吸附在刚性基质上的二肉豆蔻酰磷脂酰胆碱多层膜在所有中间相中都能达到完全水合状态。

Adsorbed to a rigid substrate, dimyristoylphosphatidylcholine multibilayers attain full hydration in all mesophases.

作者信息

Katsaras J

机构信息

National Research Council, Steacie Institute for Molecular Sciences, Neutron Program for Materials Research, Chalk River Laboratories, Chalk River, Ontario K0J 1J0, Canada.

出版信息

Biophys J. 1998 Nov;75(5):2157-62. doi: 10.1016/S0006-3495(98)77658-1.

Abstract

Whether hydrated from vapor or immersed in liquid water, aligned multibilayers of dimyristoylphosphatidylcholine adsorbed to a single mica "substrate" are shown by neutron diffraction to hydrate in all mesophases (e.g., Lbeta', Pbeta', and Lalpha) to the same extent as their liposomal counterparts suspended in liquid water. These data clearly demonstrate that the commonly accepted vapor pressure paradox does not exist.

摘要

无论是从蒸汽中吸水还是浸入液态水中,通过中子衍射显示,吸附在单个云母“底物”上的二肉豆蔻酰磷脂酰胆碱的排列多层膜在所有中间相(例如,Lβ'、Pβ'和Lα)中的水合程度与悬浮在液态水中的脂质体对应物相同。这些数据清楚地表明,普遍接受的蒸气压悖论并不存在。

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本文引用的文献

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Structure of the Lc' phase in a hydrated lipid multilamellar system.
Phys Rev Lett. 1995 May 29;74(22):4456-4459. doi: 10.1103/PhysRevLett.74.4456.
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Critical Fluctuations in Membranes.膜中的临界涨落
Phys Rev Lett. 1995 Apr 3;74(14):2832-2835. doi: 10.1103/PhysRevLett.74.2832.
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