Hoekema R, Venner K, Struijk J J, Holsheimer J
Institute for Biomedical Technology, University of Twente, AE Enschede, 7500, The Netherlands.
Comput Biomed Res. 1998 Oct;31(5):348-62. doi: 10.1006/cbmr.1998.1486.
In this paper, multilevel techniques are introduced as a fast numerical method to compute 3-D potential field in nerve stimulation configurations. It is shown that with these techniques the computing time is reduced significantly compared to conventional methods. Consequently, these techniques greatly enhance the possibilities for parameter studies and electrode design. Following a general description of the model of nerve stimulation configurations, the basic principles of multilevel solvers for the numerical solution of partial differential equations are briefly summarized. Subsequently, some essential elements for successful application are discussed. Finally, results are presented for the potential field in a nerve bundle induced by tripolar stimulation with a cuff electrode surrounding part of the nerve.
本文介绍了多级技术,作为一种用于计算神经刺激配置中三维电位场的快速数值方法。结果表明,与传统方法相比,使用这些技术可显著减少计算时间。因此,这些技术极大地增加了进行参数研究和电极设计的可能性。在对神经刺激配置模型进行一般性描述之后,简要总结了用于偏微分方程数值解的多级求解器的基本原理。随后,讨论了成功应用的一些关键要素。最后,给出了用环绕部分神经的袖带电极进行三极刺激时神经束中电位场的结果。