Junginger T, Seifert J K, Weigel T F, Heintz A, Kreitner K F, Gerharz C D
Klinik und Poliklinik fur Allgemein- und Abdominalchirurgie, Johannes-Gutenberg-Universität Mainz.
Med Klin (Munich). 1998 Sep 15;93(9):517-23. doi: 10.1007/BF03042660.
Between 1 Jan 1996 and 1 Apr 1998 29 patients underwent cryosurgical therapy for liver metastasis at the Department of Surgery at the University of Mainz.
No complications occurred following cryosurgery alone (n = 12). Within the group of patients with a combined procedure (n = 11) 1 patient had temporary liver failure and 1 patient died of sepsis. Following freezing of the cutting zone (n = 6) 1 patient showed a bile fistula and 1 ascites. In 15 cases of 28 dismissed patients with remaining destroyed tumor tissue the follow-up showed no tumor recurrence (median follow-up 11 months). On the other hand 9 patients had a tumor recurrence within the liver, 3 patients at extrahepatic regions and 7 patients developed a tumor recurrence within the freezing zone.
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